Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

The Equipment Engineer I contributes professional engineering support to the evaluation, installation, modification, and maintenance of manufacturing equipment to ensure reliable, efficient, and compliant operation. Operating within a professional scope, this role applies foundational engineering principles to assess equipment performance, support technical problem-solving, and participate in improvement initiatives that strengthen equipment reliability and operational consistency. The position collaborates with engineers, technicians, and cross-functional partners to advance technical solutions, maintain engineering documentation, and contribute to the effective execution of equipment engineering activities.

You will work on-site full-time at our office located in Durham, NC

This position works the weekend shift, Sat - Tue from 6:00am to 4:00pm

The Equipment Engineer I contributes professional engineering support to the evaluation, installation, modification, and maintenance of manufacturing equipment to ensure reliable, efficient, and compliant operation. Operating within a professional scope, this role applies foundational engineering principles to assess equipment performance, support technical problem-solving, and participate in improvement initiatives that strengthen equipment reliability and operational consistency. The position collaborates with engineers, technicians, and cross-functional partners to advance technical solutions, maintain engineering documentation, and contribute to the effective execution of equipment engineering activities.

You will work on-site full-time at our office located in Durham, NC

This position works the weekend shift, Sat - Tue from 6:00am to 4:00pm

Responsibilities:

Performs engineering analyses by collecting data, reviewing operational trends, and preparing technical observations to support evaluations of equipment performance and reliability.
Supports professional engineering activities related to installation, modification, and qualification of manufacturing equipment, ensuring alignment with established engineering standards and production requirements.
Executes advanced maintenance, repair, and technical adjustments on complex manufacturing equipment by applying extensive procedural knowledge and hands-on expertise.
Contributes to equipment troubleshooting efforts by applying engineering principles to initial assessments and collaborating on the development of corrective actions and process improvements.
Develops and maintains engineering documentation, including specifications, change records, technical instructions, and performance logs, ensuring accuracy and compliance with engineering controls.
Collaborates with engineers, maintenance personnel, and operations teams on continuous improvement initiatives that enhance equipment capability, efficiency, and reliability.
Participates in equipment testing, calibration, and verification activities to support engineering evaluations and adherence to technical standards.
Applies professional judgment within defined engineering procedures while upholding safety, quality, and regulatory requirements in all aspects of equipment engineering support.
These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

Required Qualifications:

Bachelor’s degree in mechanical engineering, electrical engineering, manufacturing engineering, or a related technical discipline.
0–2 years of relevant engineering experience, preferably in a manufacturing or production environment.
Basic understanding of mechanical, electrical, pneumatic, and control systems.
Familiarity with CAD tools, technical drawings, and engineering documentation.
Knowledge of root cause analysis methods and problem-solving techniques is preferred.
Demonstrated level of knowledge regarding applicable regulatory standards commensurate with the position's complexity and scope, contributing to organizational regulatory compliance. Minimal applicable standards for this position include:
GMP quality management systems (e.g. ISO 13485)
Clinical laboratory regulations (e.g. CAP, CLIA, NYSDOH, ISO 15189)
Operations within the regulated medical device environment (e.g. IVDD, IVDR, FDA 21 CFR 800 series, FDA 21 CFR Part 11)

Preferred Qualifications:

Analytical mindset with strong problem-solving and technical reasoning abilities.
Ability to learn and apply engineering concepts to practical manufacturing challenges.
Effective communication and collaboration skills across technical and operations teams.
Attention to detail and accuracy in documentation and data analysis.
Commitment to safety, quality, and continuous improvement principles.

Physical Demands and Work Environment:

Works primarily in a manufacturing and engineering environment with regular exposure to production areas, equipment, and occasional noise.
May require standing, walking, and occasional lifting during equipment inspections or installations.
Use of personal protective equipment (PPE) is required when working on or near production equipment.
Work may occasionally extend beyond regular hours to support maintenance or installation schedules.

The expected, full-time, annual base pay scale for this position is $69,000 - $85,000. Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

Equipment Engineer 1 (6:00am - 4:00pm Sat - Tue) # 4781