Salary Range:

CHF122,500.00 - CHF227,500.00

Band

Level 5

Job Description Summary

Job Title: Senior Principal Scientist/Principal Scientist I/II, Oncology (RLT)
#LI-Onsite
Location: Basel, Switzerland
Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible.

Shape the future of cancer treatment by driving innovative radioligand therapies from discovery to clinic. As a scientific leader within our Oncology Drug Discovery team in Basel, you will lead cutting-edge preclinical research, designing impactful in vivo studies and collaborating across global, multidisciplinary teams to unlock the potential of next-generation cancer treatments. This role offers a unique opportunity to combine scientific excellence with leadership—mentoring talent, influencing strategy, and translating complex data into meaningful insights that accelerate life-changing therapies for patients worldwide.

Job Description

Key Responsibilities

Design and lead in vivo studies supporting preclinical evaluation of radioligand therapies
Drive efficacy, biodistribution, imaging, and mechanism of action studies across oncology programs
Collaborate with cross-functional teams to advance drug candidates toward clinical development
Manage external partnerships with contract research organizations and academic collaborators
Mentor, guide, and develop scientists to strengthen scientific and professional capabilities
Present data and insights clearly to influence decisions across global research and development teams

Essential Requirements

Doctor of Philosophy in Pharmacology, Cell Biology, or a related biomedical discipline
Minimum three years of additional experience in biomedical research within academia or industry
Strong background in cancer biology with a proven track record of scientific achievement
Extensive experience designing and managing in vivo oncology studies, including efficacy and pharmacokinetic assessment
Expertise in ex vivo analysis methods such as flow cytometry, immunofluorescence, immunohistochemistry, or RNA sequencing
Demonstrated ability to collaborate effectively within multidisciplinary and global research teams
Excellent communication and presentation skills in English, both written and verbal
Self-motivated, proactive, and able to independently drive scientific projects forward

Desirable Requirements

Experience in radioligand therapy development or radiobiology
Strong understanding of drug development within oncology or related therapeutic areas

This is a dual level posting. The final level and title for this position will be determined following the completion of the candidate evaluation process, based on skills, experience, and organizational needs

Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Skills Desired

Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills, Curious Mindset, Data, Data Analysis, Decision Making, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy- Leadership, Influence, Laboratory, Lifesciences, Machine Learning (ML), Medical Research, Mentorship {+ 11 more}